I am an evolutionary biologist from Argentina, now based in Sweden. I am an Assistant Professor at the Department of Zoology, Stockholm University and a DDLS Fellow at SciLifeLab.
How has evolution generated the extraordinary diversity of life on Earth? At the heart of this question lies evolvability—the ability of organisms to generate variation. I am interested in understanding what determines evolvability and how we can use this understanding to predict evolution.
To understand evolvability, I focus on development—the dynamic process by which variation in genetic and environmental factors gives rise to differences in morphology, physiology, and behavior. By applying computational and mathematical tools of dynamical systems theory to development, I aim to uncover the principles that govern evolvability and shape the evolutionary potential of organisms.
01/01/2025: Our lab at Stockholm University and SciLifeLab has officially started! Stay tuned for open positions very soon.
12/12/2024: New paper out!
18/10/2024: Great experience presenting and discussing in Lisbon at The Genotype-Phenotype map: experimental and theoretical approaches workshop.
28/06/2024: We had a great time hosting our symposium on predicting evolution at EuroEvoDevo 2024 in Helsinki.
26/03/2024: New paper out!
2024
Utilizing developmental dynamics for evolutionary prediction and control
Milocco, L. & Uller, T.
Proceedings of the National Academy of Sciences [DOI][PDF]
The paradox of predictability provides a bridge between micro- and macroevolution
Tsuboi, M., Sztepanacz, J., De Lisle, S., Voje, K. L., Grabowski, M., Hopkins, M. J., Porto, A., Balk, M., Pontarp, M., Rossoni, D., Hildesheim, L. S., Horta-Lacueva, Q. J. B., Hohmann, N., Holstad, A., Lürig, M., Milocco, L. , Nilén, S., Passarotto, A., Svensson, E. I., Villegas, C., Winslott, C., Liow, L. H., Hunt, G., Love, A. C. & Houle, D.
Journal of Evolutionary Biology [DOI]
Twenty years on from Developmental Plasticity and Evolution: middle-range theories and how to test them
Uller, T., Milocco, L. Isanta-Navarro, J., Cornwallis, C.K. & Feiner, N.
Journal of Experimental Biology [DOI]
2023
A data‐driven framework to model the organism–environment system
Milocco, L. & Uller, T.
Evolution & Development [DOI][PDF]
2022
A method to predict the response to directional selection using a Kalman filter
Milocco, L. & Salazar-Ciudad, I.
Proceedings of the National Academy of Sciences [DOI][PDF]
Evolution of the G Matrix under Nonlinear Genotype-Phenotype Maps
Milocco, L. & Salazar-Ciudad, I.
The American Naturalist [DOI][PDF]
2020
Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps
Milocco, L. & Salazar-Ciudad, I.
Evolution [DOI][PDF]
Evolutionary development warps our expectations for the evolution of G matrices and the phenotypes they produce - Naturalist Selections podcast